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Figure 4. Estrogen receptor expression and macrophage infiltration are heightened but not correlated in male tumors. Quantification of (a) ERα, (b) <t>F480-positive</t> macrophages, and (c) CD3-positive T-cells in whole slide mammary tumors; (d) correlation of ERa and F480 intratumoral protein expression. Metrics were assessed with a student’s parametric or nonparametric test or Pearson’s correlation analysis where applicable. Bars represent 50 µm; * p ≤0.05, ** p ≤0.01, and ns = nonsignificant.
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Figure 4. Estrogen receptor expression and macrophage infiltration are heightened but not correlated in male tumors. Quantification of (a) ERα, (b) F480-positive macrophages, and (c) CD3-positive T-cells in whole slide mammary tumors; (d) correlation of ERa and F480 intratumoral protein expression. Metrics were assessed with a student’s parametric or nonparametric test or Pearson’s correlation analysis where applicable. Bars represent 50 µm; * p ≤0.05, ** p ≤0.01, and ns = nonsignificant.

Journal: International journal of molecular sciences

Article Title: Elucidating Sex-Specific Immune Profiles in a Breast Cancer Model.

doi: 10.3390/ijms252313113

Figure Lengend Snippet: Figure 4. Estrogen receptor expression and macrophage infiltration are heightened but not correlated in male tumors. Quantification of (a) ERα, (b) F480-positive macrophages, and (c) CD3-positive T-cells in whole slide mammary tumors; (d) correlation of ERa and F480 intratumoral protein expression. Metrics were assessed with a student’s parametric or nonparametric test or Pearson’s correlation analysis where applicable. Bars represent 50 µm; * p ≤0.05, ** p ≤0.01, and ns = nonsignificant.

Article Snippet: 2024, 25, 13113 13 of 17 TX, USA), and F480 (1.5 μg/mL; Cat. No. 70076S, Cell Signaling Technology, Danvers, MA, USA).

Techniques: Expressing